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Acʹme

.

The crisis of a disease. Old medical writers used to divide the progress of a disease into four periods: the ar-che, or beginning; the anabʹasis, or increase, the acʹme, or term of its utmost violence, and the pa-racʹ-me, or decline. Figuratively, the highest point of anything

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Entry taken from Dictionary of Phrase and Fable, edited by the Rev. E. Cobham Brewer, LL.D. and revised in 1895.

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