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, a physician and anatomist of the sixteenth century, was a native of Carpi in Modena, whence some biographers have called him by the name of Carpius, or Carpensis. He took his doctor’s degree at Bologna, and first taught anatomy and surgery at Pavia. He afterwards returned to Bologna in 1520, and taught the same studies. He was there, however, accused of having intended to dissect two Spaniards who had the venereal disorder, and had applied to him for advice, which, it was said, he meant to perform while they were alive, partly out of his hatred to that nation, and partly for his own instruction. Whatever may be in this report, it is certain that he was obliged to leave Bologna, and retire to Ferrara, where he died in 1550. By his indefatigable attention to the appearances of disease, and especially by his frequent dissections, which in his time, were quite sufficient, without any other demerit, to raise popular prejudices against him, he was enabled to advance the knowledge of anatomy by many important discoveries. His works were, 1. “Commentaria, cum amplissimis additionibus, super anatomia Mundini,” Bologna, 1521, 1552, 4to, and translated into English by Jackson, London, 1664. 2. “Isagogtc breves in anatomiam corporis humani, cum aliquot figuris anatomicis,” Bologna, 1522, 4to, and often reprinted. 3. “De Cranii fractura, tractatus,” Bologna, 1518, 4to, also often reprinted. He was one of the first who employed mercury in the cure of the venereal disease.

, a Swiss physician and anatomist of eminence, was born at Diessenhofen, the 16th of January, 1653. After passing through the usual school education, he was sent, at the age of sixteen, to Strasburgh, where, applying assiduously to the study of physic and anatomy, he was created doctor in medicine in 1672. For his thesis, he gave the anatomy of a child with two heads, which he met with. He now went to Paris, and attended the schools and hospitals there with such assiduity, as to attract the notice, and gain him the intimacy of Dionis and du Verny, who were present while he made the experiments on the pancreas, which enabled him, some years after, to publish a more accurate description of that viscus, than had been before given, under the title of “Experimenta nova circa Pancreas. Accedit Diatribe de Lympha et genuine Pancreatis usu,” Leidse, 1682, 8vo. He proved that the fluid secreted by the pancreas is not necessary to digestion, and that an animal may live after that viscus is taken out of the body, having tried the experiment upon a dog, which perfectly recovered from the operation. On quitting Paris, he came to London, and was introduced to Dr. Willis, Lower, and Henry Oldenburg, secretary to the royal society. From England he passed to Holland, and studied for some months at Leyden. At Amsterdam he visited Swammerdam and Ruysch, with whom he afterwards corresponded. Returning home he was made professor of medicine at Heidelberg, and first physician to the elector palatine, who conferred on him the title of baron de Brunn in Hamerstein. About the same time, he niarried one of the daughters of the celebrated Wepfer, and was elected honorary member of the academia naturae curios, in return for some ingenious dissertations which he had communicated to them. In 1688 he publised “Dissertatio Anatomica de Glandula pituitaria,” Heidelb. 4to. From this time he became in such great request for his knowledge and success in practice, that he was, in succession, consulted by most of the princes in Germany. Among others, in 1720, he was sent for to Hanover, to attend the prince of Wales, afterwards king George II. In 1715 he published at Heidelberg, “Glandula Duodeni sen Pancreas secundum detectum,” 4to, which was only an improved edition of his “De Glandulis in Duodeno Intestino detectis,” which had been before twice printed. There are some other lesser works, the titles and accounts of which are given by Haller, in his Bib. Anat. In the latter edition of Wepfer’s works are given dissections by our author, of the heads of some persons who died of apoplexy, of whom he had had the care. Though early afflicted with gravel, and in the latter part of his life with gout, he continued to attend to the calls of his patients, though living a great distance from his residence. When in his 74th year, he went in great haste to Munich, to attend the elector Maximilian Emanuel; on his return, he was seized with a fever, which, in a few days, put an end to his life, October 2, 1727.

, a most celebrated physician and anatomist of Italy, was descended from a noble family, and born at Modena, most probably in 1523, although some make him born in 1490. He enjoyed a strong and vigorous constitution, with vast abilities of mind, which he cultivated by an intense application to his studies in philosophy, physic, botany, and anatomy. In this last he made some discoveries, and, among the rest, that of the tubes by which the ova descend from the ovarium, and which from him are called the “Fallopian tubes.” He travelled through the greatest part of Europe, and penetrated by his labour the most abstruse mysteries of nature. He practised physic with great success, and gained the character of one of the ablest physicians of his age. He was made professor of anatomy at Pisa in 1548, and was promoted to the same office at Padua in 1551; at which last place he died October 9, 1563, according to the common opinion, in the prime of life, but not so, if born in 1490.

, a physician and anatomist, mentioned in the preceding lite, was born at Fordingbridge, in Hampshire, Feb. 6, 1613, and educated at Oxford, where he was elected a scholar of Trinity college in 1632, and took his degree of M. D. in 1642. After this he practised at Sherbourne, in Dorsetshire, with a considerable share of reputation, and died there March 21, 1684. He was buried at Candle Purse in that county, of which place his lather had been rector. Though wiih limited opportunities of dissection, he pursued the study of anatomy with zeal, and his name has been given to some discoveries not strictly his; as that of the ant mm inaxillare, of which he obtained a view from an extracted tooth, which suggested the operation of piercing into it from the jaw, practised by Cowper. Casserius had mentioned the cavity under the name of ant rum gente. His principal work is, “Corporis Humani Disquisitio Anatomica,” printed at the Hague in 1651, in folio, the descriptions in which are too. brief, the reasonings unnecessarily copious, and the figures chiefly copied from Vesalins. His other writings are, “Exercitationes cliuc, quanun prior de passione hysterica, altera de affectione hypochondnaca,” Oxon. 1660, abounding with physiological remarks and hypotheses, some of which are ingenious, but being attacked by Dr. Willis, Highmore printed, in H,70, “De hysterica et hypochondriaca passione, Responsio Epistolaris ad Willisium.” “A History of Generation,” 8vo, 1651, which has some good figures of the embryo in the egg, during the state of incubation; “Considerations on the Scarborough Spa,” and “Accounts of the Springs at FarinHon r.nd East Chennock,” both in the Philosophical Transactions.

LflEUTAUD (Joseph), a celebrated physician and anatomist, was born at Aix, in Provence, June 21, 1703. His family, long established at Aix, had produced many distinguished officers, ecclesiastics, lawyers, &c. He was at first intended by his parents for the church; but the reputation of his maternal uncle Garidel, the professor of medicine at Aix, gave him a bias to the study of medicine, and particularly botany, in which his researches and skill soon occasioned him to be promoted to the chairs of botany and anatomy at Aix, which his uncle had long filled. His lectures on anatomy were much attended, and by an audience comprising many persons not engaged in the study of medicine, and among others, the marquis d'Argens, the intimate friend of the king. M. Lieutaud published, in 1742, a syllabus of anatomy for the use of his pupils, entitled “Essais auatomiques, contenant l'Histoire exacte de toutes les parties qui composent le corps humaine;” it was several times reprinted, with improvements, and in 1777 was edited by M. Portal, in 2 volumes. He communicated also several papers on morbid anatomy, and on physiology, to the academy of sciences, of which he was elected a corresponding member. In 1749, however, he quitted his post at Aix, and went to Versailles, at the instance of the celebrated Senac, who then held the highest appointment at court, and who obtained for Lieutaud the appointment of physician to the royal infirmary. This act of friendship is said to have originated from the private communication of some errors, which Lieutaud had detected in a work of M. Senac, and which he did not deem it proper to publish. At Versailles he continued his anatomical investigations with unabated zeal, and was soon after his arrival elected assistant anatomist to the royal academy, to which he continued to present many valuable memoirs. He also printed a volume entitled “Elementa Physiologice,” &c. Paris, 1749, which had been composed for the use of his class at Aix. In 1755, he was nominated physician to the royal family; and twenty years afterwards, he obtained the place of first physician to the king, Louis XVI. In 1759 he published a system of the practice of medicine, under the title of *' Precis de la Medicine pratique,“which underwent several editions, with great augmentations, the best of which is that of Paris, 1770, in 2 vols. 4to. In 1766, he published a” Precis de la Matiere medicale,“in 8vo, afterwards reprinted in 2 vols. But his most important work, which still ranks high in the estimation of physicians, is that which treats of the seats and causes of diseases, ascertained by his innumerable dissections. It was entitled” Historia Anatomico-medica, sistens numerosissima cadaverum humanorum extispicia," Paris, 1767, in 2 vols. 4to. M. Lieutaud died September 6, 1780, after an illness of five days.

, an eminent physician and anatomist, was born at Tremere, in Cornwall, about 1631. He was descended from a good family, and received a liberal education, being admitted as king’s scholar at Westminster school, and thence elected to Christ-church college, Oxford, in 1649, where he took the degree of M. A. in 1655, and then studied medicine. The celebrated Dr. Willis, who employed him as coadjutor in his dissections, found him so able an assistant, that he afterwards became his steady friend and patron, and introduced him into practice. In 1665, Lower took the degree of M. D.; and in the same year published a defence of Dr. Willis’s work on fevers, entitled “Diatribae Thomae Willisii M. D. et Prof. Oxon. de Febribus Vindicatio adversus Edm. de Meara Ormondiensem Hibern. M. D.” 8vo, a work of considerable learning and force of argument, but not without some fallacies, as he afterwards himself admitted. But his most important work was, his “Tractatus de Corde, item de motu et calore Sanguinis, et Chyli in eum transitu,” which was first printed in London in 1669. In this work the structure of the heart, the origin and course of its fibres, and the nature of its action, were pointed out with much accuracy and ingenuity. He likewise demonstrated the dependance of its motions upon the nervous influence, referred the red colour of the arterial blood to the action of the air upon it in the lungs, and calculated the force of the circulation, and the quantity and velocity of the blood passing through it. The work excited particular notice, in consequence of the chapter on the transfusion of blood from the vessels of one living animal to those of another, which the author had first performed experimentally at Oxford, in February 1665, and subsequently practised upon an insane person before the royal society. Lower claims the merit of originality in this matter; but the experiment had certainly been suggested long before by Ia­bavius (see Libavius), and experience having soon decided, that the operation was attended with pernicious consequences, it was justly exploded. Lower had removed to London soon after the commencement of these experiments, and in 1667 had been a fellow of the royal society, and of the college of physicians. The reputation acquired by his publications brought him into extensive practice and after the death of Dr.- Willis,. he was considered as one of the ablest physicians in London. But his attachment to the Whig party, at the time of the Popish plot, brought bun iufao discredit at court, so that his practice dedlned considerably before his death, Jan 17, 1690-91. He was buried at St. Tudy, near his native place, in Cornwall, where he had purchased an estate. In addition to the writings above-mentioned, he communicated some papers containing accounts of anatomical experiments to the royal society; a small tract on catarrh, which was added, as a new chapter, to the edition of the treatise de Corde of 1680; and a letter on the state of medicine in England. He is said to have been the first discoverer of Astrop Wells.

, an Italian physician and anatomist, was born March 10, 1628, at Crevalcuore, near Bologna, in Italy, where he was taught Latin and studied philosophy. In 1649, losing his parents, and being obliged to choose his own method of life, he determined to apply himself to physic. The university of Bologna was then supplied with very learned professors in that science, particularly Bartholomew Massari, and Andrew Mariano, under whose instructions Malpighi in a short time made great progress in physic and anatomy. After he had finished the usual course, he was admitted doctor of physic, April 6, 1653, In 1655 Massari died, a loss which Malpighi severely felt, as independent of his esteem for him as a master, he had become more nearly related to him by marrying his sister. In 1656, the senate of Bologna gave him a professorship, which he did not long hold; for the same year the grand duke of Tuscany invited him to Pisa, to be professor of physic there. Here he contracted a strict friendship with Borelli, whom he subsequently owned for his master in philosophy, and to whom he ascribed all the discoveries which he afterwards made. They dissected animals together, and it was in this employment that he found the heart to consist of spiral fibres; a discovery, which has been ascribed to Borelli in his posthumous works. The air of Pisa not agreeing with Malpighi, be continued there but three years: and, in 1659, returned to Bologna, to resume his former posts, notwithstanding the advantageous offers which were made him to stay at Pisa. In 1662 he was sent for to Messina, in order to succeed Peter Castello, first professor of physic, who was just dead. It. was with reluctance that he went thither, though the stipend was great; and although he was prevailed on at last by his friend Borelli, to accept it, yet in 1666 he returned to Bologna. In 1669 he was elected a member of the royal society of London, with which he ever after kept a correspondence by letters, and communicated his discoveries in anatomy. Cardinal Pignatelli, who had known him while he was legate at Bologna, being chosen pope in 1691, under the name of Innocent XII. immediately sent for him to Rome, and appointed him his physician. In 1694 he was admitted into the academy of the Arcadians at Rome. July the 25th, of the same year, he had a fit, which struck half his body with a paralysis; and, November the 29th following, he had another, of which he died the same day, in his 67th year. His remains were embalmed, and conveyed to Bologna, where they were interred with great funeral honours in the chureh of St. Gregory, and a statue was erected to his memory. Malpighi is described as a man of a serious and melancholy temperament, which is confirmed by his portrait in the meeting-room of the royal society at Somerset-house. He was indefatigable in the pursuit of knowledge, on the sure ground of experience and observation, ever candid in his acknowledgments to those who had given him any information, and devoid of all ostentation or pretension on the score of his own merits. He ranks very high among the philosophers of the physiological age in which he lived, when nature began to be studied instead of books, and the dreams of the schools. Hence arose the discoveries of the circulation of the blood, the absorbent system of the animal body, and the true theory of generation. To such improvements the investigations of Malpighi, relative to the anatomy and transformation of insects, particularly the silk-worm, and the developement of the chick in the egg, lent no small aid. From these inquiries he was led to the anatomy and physiology of plants, in which he is altogether an original, as well as a very profound, observer. His line of study was the same as that of Grew, but these philosophers laboured independent of each other, and their frequent coincidence evinces the accuracy of both.

, a physician and anatomist of eminence, was born in London in 1699, where his father was a barrister. After receiving the rudiments of his education at a private school in the country, where his docility and sweetness of temper endeared him to his master and school- fellows, he was in a few years removed to Westminster, and thence to Oxford, where he was admitted a commoner of Exeter college, under the tuition of Mr. John Haviland, in 1714. He applied himself to the usual academical exercises with great assiduity, and took his degrees in arts at the accustomed periods, that of M. A. in 1721. He paid his greatest attention to natural philosophy, and after reading a few books on anatomy, engaged in dissections, which he pursued with so much reputation as to be chosen reader of anatomy in the university in 1726, about two years after taking his degree of B. M. In this office he used his utmost endeavours to introduce a zeal for this neglected study, and obtained a high and well merited reputation. His residence at Oxford, however, was only temporary; for at the close of his course he returned to London, where he bad determined to settle, after having made a short trial of practice in Cornwall, and a subsequent visit to the principal schools of France and Italy. At Paris, by conversing freely with the learned, he soon recommended himself to their notice and esteem. Winslow’s was the only good system of physiology at that time known in France, and Morgagni’s and Santorini’s, of Venice, in Italy. On his return to England he resumed his anatomical and physiological lectures in London, and they were frequented, not only by students from both the universities, but by many surgeons, apothecaries, and others. His reputation rapidly extended, and in 1728 he was elected a fellow of the royal society, to which he communicated several papers, which were published in the Philosophical Transactions, especially some observations on the nature of aneurisms, in which he controverted the opinion of Dr. Freind; and a description of a singular disease, in which the pulmonary vein was coughed up. He also made observations on a treatise by Helvetius, on the lungs. In 1729, he received the degree of M. D at Oxford, and became a fellow of the college of physicians in. 1732. In 1734 he was appointed to read the Gulstonian lectures at the college, and chose the structure of the heart, and the circulation of the blood, for his subjects. At the request of the president, Dr. Nichols again read the Gulstonian lectures in 1736, choosing for his topics the urinary organs, and the nature and treatment of calculous diseases; and in 1739 he delivered the anniversary Harveian oration. In 1743 he married one of the daughters of the celebrated Dr. Mead, by whom he had a son and daughter, both living.

, a distinguished Dutch physician and anatomist, but a German by birth, was greatly distinguished by his anatomical labours, both at the Hague and at Leyclen, in the latter part of the seventeenth cenr tury. He filled the office of professor of anatomy and surgery in the university of Leyden, and was also president of the college of surgeons. He pursued his dissections with great ardour, cultivating both human and comparative anatomy at every opportunity. In these pursuits, within eight years he dissected above sixty human bodies, besides those of the animal creation, and made many discoveries by means of injections, but at that time this art had not attained its full perfection, quicksilver being the only substance used. He died about 1692. The following is a catalogue of his publications: “De Vasis aquosis Oculi,” Leid. 1685;“De Ductu salivali novo, Salivfi, ductibus aquosis et humore aqueo oculorum,” ibid. 1686. Some subsequent editions of this work were entitled “Sialographia, et ductuum aquosorum Anatome nova;” “Adenographia curiosa, et Uteri foeminei Anatome nova, cum Epistola ad Amicum de Inventis novis,” ibid. 1692, &c. “Operationes et Experirnenta Chirurgica,” ibid. 1692, and frequently reprinted. The three last mentioned works were published together in 3 vols. 12 mo, at Lyons, in 1722. There are some Mss. under his name in the British Museum, in Ayscough’s Catalogue, but they do not appear to be originals.

, or in Latin Pavius, a physician and anatomist, born at Amsterdam in 1564, was educated in medical studies at Leyden, whence he proceeded to Paris for farther improvement. He afterwards spent some time in Denmark, and at Rostock, where he received the degree of doctor in 1587, and at Padua. On his return to Leyden, he was appointed professor of medicine in 15S9, in which office he acquired the approbation and esteem both of the public and his colleagues, and died universally regretted, in August 1617, at the age of fifty-four. Anatomy and botany were the departments which he most ardently cultivated; and he was the founder of the botanic garden of Leyden. His works are, 1. “Tractatus de Exercitiis, Lacticim'is, et Bellariis.” Rost. 2. “Notse in Galen urn, de cibis boni et mali succi,” ibid. These two pieces appear to. have been his inaugural exercises. 3. “Hortus publi-, cus Academiae Lugduno-Batavae, ejus Ichnographia, descriptio, usus, &c.” Lugd. Bat. 1601. 4. “Primitioe Anatomicae de humani corporis Ossibus,” ibid. 1615. 5. “Succenturiatus Anatomicus, continens Commentaria in Hip-. pocratem de Capitis Vulneribus. Additae sunt Anuotationes in aliquot Capita Librioctavi C. Celsi,” ibid. 1616. 6. “Notae et Commentarii in Epitomen Anatomicum Aridresa Vesalii, ibid, 1616. To these we may add some works which appeared after his death. 7.” De Valvula Intestini Epistolaa du33.“Oppenheim, 1619, together with the first century of the Epistles of Fabric-ills Hildanus. 3.” De Peste Tractatus, cum Henrici Florentii additamentis.“Lug. Bat. 1636. 9.” Anatomicae Observationes selectiores.“Hafniae, 1657, inserted in the third and fourth centuries of the anatomical and medical histories of T. Bartholin. He also left in ms. a” Methodus Anatomica," which was in the library of M. de Vick of Amsterdam.

, the Ephesian, a physician and anatomist in the reign of the emperor Trajan, obtained great reputation by his extensive knowledge and experience. Galen esteemed him one of the most able of the physicians who had preceded bin:-. Rufus appears to have cultivated anatomy, by dissecting brutes, with great zeal and success. He traced the origin of the nerves in the brain, and considered some of them as contributing to motion, and others to sensation. He even observed the capsule of the crystalline lens in the eye. He considered the heart as the seat of life, and of the animal heat, and as the origin of the pulse, which he ascribed to the spirit of its left ventricle and of the arteries; and he remarked the difference in the capacity and thickness of the two ventricles. He deemed the spleen to be a very useless viscus, and his successors have never discovered its use. He examined very fully the organs of generation, and the kidnies and bladder; he has left, indeed, a very good treatise on the diseases of the urinary organs, and the methods of cure. He also wrote a work on purgative medicines, mentioning their different qualities, the countries from which they were obtained; and a little treatise on the names given by the Greeks to the different parts of the body. Galen affirms also that Rufus was the author of an essay on the tnateria medica, written in verse; and Suidas mentions a treatise of his on the ' atra bilis, with some other essays; but these are lost. What remains of his works are to be found in the “Artis medicse principes” of Stephens, and printed separately at London, Gr. and Lat. 4to, by W. Clinch, 172G.

, a physician and anatomist, was born in 1643 at Vesbrouck, in the county of Waes. He was descended of a family who had many years subsisted from the profits arising from the cultivation of the earth; and he had himself worked with the spade to the age of twenty-two years; when the curate of his village, taking notice of him, gave him the first rudiments of learning. He afterwards obtained a place in the college of the Trinity at Louvain, where he was made professor of anatomy in 16y, and afterwards doctor in medicine. He died there in Feb. 1710, aged 62. The following epitaph was found after his decease, written with his own hand: “Philippus Vt-rheyen Medicina; Doctor & Professor, partem sui materialem hie in Cremeterio condi voluit, ne Templum dehonestaret, am nocivis halitibus inficeret. Requiescat in pace.”

, a physician and anatomist, was born in 1641, at the village of Rovergue, and after studying and taking his degrees in medicine at Montpellier, settled there as a practitioner. In 1671, he was appointed physician to the hospital of St. Eloy, where from frequent opportunities of anatomical dissection, he was led to pay particular attention to the subject of neurology, which, notwithstanding what the celebrated Dr. Willis had published, was a part of the animal economy very little known. After ten years study of the nerves, he published the work which has redounded most to his honour, “Neurologia universalis, hoc est, omnium huniani corporis nervorum, simul ac cerebri, medullaeque spinalis, descriptio anatomica,” Leyden, 1685, fol. Even of this work, however, the anatomical part is the most valuable, for what respects the physiology, which forms a considerable part of the volume, deserves very little regard, as being founded on wrong principles. He afterwards published other anatomical works, but does not appear to have advanced his reputation by them. Astruc and Senac have given a very unfavourable account of his genius and judgment, yet neither can deny that his anatomical researches have been of service. In 1690 he was sent for to be physician to mademoiselle de Montpensier, but at her death returned to Montpellier, where he died in 1716.