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, son of the former by his first wife, was born at Altdorf in 1653; and sent to school at Herszpi uck, where having acquired a competent knowledge of the Greek and Latin tongues, he returned to his father at Altdorf at the age of sixteen, and studied first philosophy, and then physic. He went afterwards to Francfort upon the Oder, and proposed to visit the United Provinces and England; but being prevented by the wars, he went to Padua, where he studied two years. Then making a tour of part of Italy, he returned to Altdorf, in 1674, and was admitted to the degree of M. D. He spent two years in adding to the knowledge he had acquired; and then, in 1677, was made professor extraordinary in physic, which title, in 1681, was changed to that of professor in ordinary. He how applied himself earnestly to the practice of physic; and in time his fame was spread so far, that he was sought by persons of the first rank. George Frederic, marquis of Anspach, of the house of Brandenbourg, chose him in 1695 for his physician; and about the latter end of the year, Hoffman attended this prince into Italy, and renewed his acquaintance with the learned there. Upon the death of his father in 1698, he was chosen to succeed him in his places of botanic professor and director of the physic garden. He was elected also the same year rector of the university of Altdorf; a post which he had occupied in 1686. He lost his great friend and patron, the marquis of Apspach, in 1703; but found the same kindness from his successor William Frederic, who pressed him so earnestly to come nearer him, and made him such advantageous otFers, that Hoffman in 1713 removed from Altdorf to Anspach, where he died in 1727. He had married a wife in 16I, by whom he bad 6ve cbildren. He left several works of repute: viz. two dissertations on anatomy and physiology; one on what has since been called morbid anatomy, entitled “Disquisitio corporis human! Anatomico-Pathologica;” ibid. 1713. “Acta Laboratorii chemici Altdorffini,” 1719. “Syntagma Pathologico-therapeuticum,” 1728, in 2 vols. 4to, and “Sciagraphia Institutionum Medicarum,” a posthumous publication. He also continued his father’s “Florre Altdorffinae.”