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was the son of Galeoti Picus, the eldest brother of John Picus,

, was the son of Galeoti Picus, the eldest brother of John Picus, just recorded, and born fcbout 1409. He cultivated learning and the sciences, after the example of his uncle; but he had dominions and a principality to superintend, which involved him in great troubles, and at last cost him his life. Upon the death of his father, in 1499, he succeeded, as eldest son, to his estates; but was scarcely in possession, when his brothers Louis and Frederic combined against him; and, by the assistance of the emperor Maximilian I. and Hercules I. duke of Ferrara, succeeded. John Francis, driven from his principality in 1502, was forced to seek refuge in different countries for nine years; till at length pope Julius II. becoming master of Mirandula, put to flight Frances Trivulce, the widow of Louis, and re-established John Francis in 1511. But he could not long maintain his post; for the pope’s troops being beaten by the French at Ravenna, April 11, 1512, John James Trivulce, general of the French army, forced away John Francis again, and set up Frances Trivulce, who was his natural daughter. John. JFrancis now became a refugee a second time, and so continued for two years; when, the French being driven out of Italy, he was restored again in 1515. He lived from that time in the quiet possession of his dominions, till October 1533; and then Galeoti Picus, the son of his brother Louis, entered his castle by night with forty armed men, and assassinated him, with his eldest son Albert Picus. He died embracing the crucifix, and imploring pardon of God for his sins,