Poxed or clapped. He was sent out a sacrifice, and came home a burnt offering; a saying of seamen who have caught the venereal disease abroad. He has burnt his fingers; he has suffered by meddling.
Definition taken from The 1811 Dictionary of the Vulgar Tongue, originally by Francis Grose.
See also the definition in Nathan Bailey's 1736 dictionary of canting and thieving slang.
Burner-1 * BurrNathan Bailey's 1736 Dictionary of canting and thieving slang
John S. Farmer's collection of canting songs and slang rhymes