To hound a person is to persecute him, or rather to set on persons to annoy him, as hounds are let from the slips at a hare or stag.
“As he who only lets loose a greyhound out of the slip is said to hound him at the hare.”—Bramhall.
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Entry taken from Dictionary of Phrase and Fable, edited by the Rev. E. Cobham Brewer, LL.D. and revised in 1895.