Guise, Henry I., third Duke of, son of Francis; the murder of his father added fresh zeal to his inborn hatred of the Protestants, and throughout his life he persecuted them with merciless rigour; he was a party to the massacre of St. Bartholomew (1572); his ambitious designs on the crown of France brought about his assassination (1550‒1588).
Definition taken from The Nuttall Encyclopædia, edited by the Reverend James Wood (1907)
Guise, Francis * Guise, Henry II.